Plasma levels of intestinal fatty-acid binding protein (I-FABP), abdominal distension and hydrogen concentration after lactitol small intestinal bacterial overgrowth (SIBO) test / Niveles plasmáticos de intestino proteína fijadora de ácidos grasos (I-FABP), distensión abdominal y concentración de hidrógeno después del lactitol intestino delgado prueba de sobrecrecimiento bacteriano (SIBO)

Breath tests with glucose, lactulose or lactitol are useful for diagnosis of small intestinal bacterial overgrowth (SIBO). Nevertheless, they have suboptimal sensitivity and specificity and, indeed, are positive in a considerable number of patients with irritable bowel syndrome (IBS). The complexity in the management of patients with functional intestinal disorders and the availability of these tests are leading to frequent diagnoses of SIBO. Intestinal Fatty-Acid Binding protein (I-FABP) is a protein present in the cytosol of intestinal epithelial cells. Its plasmatic levels have been related to different enteropathies and, therefore, could be a marker of early intestinal damage with unconfirmed clinical utility. Hence, we have studied the plasmatic I-FABP level of patients who are requested a lactitol test to confirm SIBO and related it to clinical and laboratory characteristics and SIBO test results.(AU)

Plasma levels of intestinal fatty-acid binding protein (I-FABP), abdominal distension and hydrogen concentration after lactitol small intestinal bacterial overgrowth (SIBO) test.

Breath tests with glucose, lactulose or lactitol are useful for diagnosis of small intestinal bacterial overgrowth (SIBO). Nevertheless, they have suboptimal sensitivity and specificity and, indeed, are positive in a considerable number of patients with irritable bowel syndrome (IBS). The complexity in the management of patients with functional intestinal disorders and the availability of these tests are leading to frequent diagnoses of SIBO. Intestinal Fatty-Acid Binding protein (I-FABP) is a protein present in the cytosol of intestinal epithelial cells. Its plasmatic levels have been related to different enteropathies and, therefore, could be a marker of early intestinal damage with unconfirmed clinical utility. Hence, we have studied the plasmatic I-FABP level of patients who are requested a lactitol test to confirm SIBO and related it to clinical and laboratory characteristics and SIBO test results.

Immunohistochemical and ultrastructural evidence of functional organization along the Corydoras paleatus intestine.

The Neotropical catfish, Corydoras paleatus (Callichthyidae) is a facultative air-breathing teleost that makes use of the caudal portion of the intestine as an accessory air-breathing organ. This portion is highly modified, being well vascularized with capillaries between epithelial cells, which makes it well suited for gas exchange. Instead, the cranial portion is a digestion and absorption site, as it has a typical intestinal epithelium with columnar cells arranged in a single row, villi and less vascularized tunica mucosa. Therefore, the intestine was studied by light and electron microscopy to assess differences between the cranial, middle and caudal portions. To characterize the potential for cell proliferation of this organ, we used anti-proliferating cell nuclear antigen antibody and anti-Na(+) K(+) -ATPase monoclonal antibody to detect the presence of Na(+) /K(+) pump. In C. paleatus it was observed that cell dynamics showed a decreasing gradient of proliferation in cranio-caudal direction. Also, the intestine of this catfish is an important organ in ionoregulation: the basolateral Na(+) /K(+) pump may have an active role, transporting Na(+) out of the cell while helping to maintain the repose potential and to regulate cellular volume.

Prevalencia de crisis asmática en pacientes pediátricos de 5 a 14 años atendidos en la Emergencia Pediátrica de la Clínica Maison de Santé - Lima. Enero a noviembre, 2015 / Prevalence of asthmatic crisis in pediatric patients of 5 to 14 years attended at the Pediatric Emergency of the Clinic Maison de Sante - Lima. January to November, 2015

La crisis de asma es una de las causas de importancia de morbilidad y mortalidad en los pacientes pediátricos así como un gran coste en la salud y economía de la familia y de la sociedad por tal motivo es importante tener la prevalencia de la crisis de asma en pacientes pediátricos entre los 5 a 14 años la clasificación e identificación adecuada y un manejo terapéutico oportuno a las misma. Objetivos: Determinar la prevalencia de crisis asmática aguda en pacientes pediátricos de 5 a 14 años atendidos en el servicio de emergencia pediátrica de la Clínica Maison de Santé - Lima (CMSL) y si su atención cumple con los estándares de las guías internacionales. Material y métodos: El estudio es un diseño observacional, retrospectivo de casos. Se revisaron, de enero a noviembre del 2015, las historias clínicas de pacientes que acudieron al Servicio de Emergencias de la CMSL por crisis asmáticas entre las edades de 5 a 14 años. Los datos se recolectaron en una base de datos Excel 2010 y se procesaron con el paquete estadístico Epi Info. Resultados: Se ha podido determinar que la prevalencia de crisis de asma leve es de 131 (71.6 por ciento) y de crisis de asma moderada 52 (28.4 por ciento) en 183 casos revisados en el período de 11 meses y que tiene un promedio de 16 casos por mes con una mayor prevalencia en los meses de junio y noviembre. Los síntomas asociados con crisis asmática más frecuentes fueron la tos con 89 (48.6 por ciento) casos, seguida de 46 (25.1 por ciento) casos que acudieron por presentar dificultad respiratoria, 27 (14.2 por ciento) casos con rinorrea y solo 21 (12 por ciento) presentó fiebre. El tratamiento establecido para las crisis de asma leve fue fenoterol en nebulización con una frecuencia de 75 (57.7 por ciento), seguido por dexametasona con una frecuencia de 26 (20.0 por ciento) en los casos atendidos. En la crisis de asma moderada se administró terapia múltiple con fenoterol más hidrocortisona o fenoterol más dexametasona en 29 (55.8...

The asthma flare - ups is one of the important causes of morbidity and mortality in pediatric patients as well as a great cost in health and economics of the family and society for this reason is important to the prevalence of asthma flare - up in pediatric patients aged 5 to 14 years classification and properly identification and appropriate therapeutic management to the same. Objectives: To determine the prevalence of acute asthma in pediatric patients aged 5 to 14 years treated in the pediatric Emergency Clinic Maison de Sante - Lima and if your care meets the standards of international guidelines. Methods: Review of children with asthmatic exacerbations at the pediatric emergency department from January to November 2015. Results: It has been determined that the prevalence of crisis mild asthma is 131 (71.6 per cent) and crisis of moderate asthma 52 (28.4 per cent) of 183 cases reviewed in the period of 11 months and has an average of 16 cases per month with a higher prevalence in the months of June and November. Symptoms associated with more frequent asthma attack was cough with 89 (48.6 per cent) cases, followed by 46 (25.1 per cent) cases that went to present respiratory distress, 27 (14.2 per cent) cases with rhinorrhea and only 21 (12 per cent) presented fever. The established treatment for mild asthma crisis was fenoterol nebulized with a frequency of 75 (57.7 per cent), followed by dexamethasone at a frequency of 26 (20.0 per cent) in the cases treated. In the crisis of moderate asthma therapy plus hydrocortisone multiple fenoterol or fenoterol plus dexamethasone in 29 (55.8 per cent) cases it was administered nebulized fenoterol followed by a frequency of 15 (28.8 per cent) cases Conclusions: It is concluded that the crisis prevalence of mild asthma is 131 (71.6 per cent) and crisis of moderate asthma 52 (28.4 per cent) of 183 cases reviewed thus cases of asthma attacks in pediatric patients still present in a significant number. Despite the...